An orally disintegrating tablet (ODT) formulation of sebetralstat, an investigational on-demand treatment for swelling attacks in hereditary angioedema (HAE) patients, is processed by the body in a similar way to its film-coated tablets, according to data from a Phase 1 clinical trial. Researchers are investigating these ODT tablets…
Patients with hereditary angioedema (HAE) are more likely to develop comorbidities, or co-existing conditions, such as cardiovascular and autoimmune diseases than the general population, a Swedish database study reports. The findings highlight the need for awareness and prevention of these conditions in patients with HAE, according to researchers. The…
Strategies to manage discontinuing attenuated androgens — male hormones frequently used as a preventive treatment for hereditary angioedema (HAE) — can be very diverse, and the most common withdrawal challenge is an increase in HAE attacks, a recent case series reported. Its authors, some of which are leading European…
A 14-year-old boy developed angioedema of the tongue thought to be triggered by Haldol (haloperidol), an antipsychotic medication used to treat schizophrenia and other mental or mood disorders, a case report found. “Clinicians should be aware of potential dangerous adverse effects of commonly used medications. Patients with angioedema may…
Effexor XR (venlafaxine), a medication normally used to treat depression and anxiety, might have triggered acute allergic angioedema in an 81-year-old woman, a case study reports. Her symptoms, including tongue swelling, nausea, vomiting, and headaches, eased after she went off Effexor XR and was treated with diphenhydramine, an anti-allergy…
HAE International (HAEi) has expanded its free online training platform to include new courses on advocacy, disease-related information, and resources. “The HAEi Advocacy Academy is the premier online learning platform for the HAE Community,” Fiona Wardman, the non-profit’s chief regional patient advocate, said in a press release.
Pharming Group has signed an exclusive license agreement with NewBridge Pharmaceuticals to distribute and commercialize Ruconest (conestat alfa), a treatment for acute attacks of hereditary angioedema (HAE), in the Middle East and North Africa. Under the agreement terms, NewBridge in collaboration with Pharming, will provide access…
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