FAQs about alternative HAE symptoms

In hereditary angioedema (HAE) the main symptom that can cause serious medical problems is swelling, which is why swelling attacks are usually the focus of treatment. However, HAE can cause a range of non-swelling symptoms even when there isn’t any swelling. It is recommended that people with HAE consult with their clinical care team about any of their symptoms.

Without treatment, swelling and other symptoms of hereditary angioedema (HAE) attacks tend to go away after a couple of days. Treatments are available that can help resolve attacks faster. Some HAE symptoms can pose life-threatening danger, such as swelling in the throat that affects breathing. When this happens, getting treated immediately is critical.

Hereditary angioedema (HAE) affects everyone differently. Essentially all people with HAE have swelling attacks, but the frequency and severity of these attacks can vary widely. People with HAE may also have non-swelling symptoms that accompany attacks or occur without any swelling, these can also be different from person to person.

In addition to swelling, people with hereditary angioedema (HAE) may have symptoms such as fatigue, headache, nausea, vomiting, redness in the skin, unusual sensations like tingling or prickling, flu-like symptoms, abdominal pain, and emotional changes like irritability or anxiety.

If you experience new or worsening symptoms of hereditary angioedema (HAE), you should talk to your healthcare provider as soon as possible. Breathing difficulty, in particular, could be an emergency situation.