A 7-year-old girl in Iran with repeated episodes of unexplained swelling was ultimately diagnosed with hereditary angioedema (HAE) after bruise-like discoloration appeared around one eye and then developed into swelling on one side of her face, according to a case report. Laboratory testing confirmed that the girl had type…
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People with hereditary angioedema (HAE) often have misgivings about the long-term safety and feasibility of preventive treatments, so it’s crucial that their doctors stay up to date on research and guidelines to provide accurate information and facilitate collaborative treatment decisions, a study found. “This research highlights the need to…
Different types of COVID-19 vaccines may produce distinct long-term immune responses in people with hereditary angioedema (HAE), according to a small study of four patients. Researchers found that all participants developed antibodies against SARS-CoV-2 — the virus that causes COVID-19 — after vaccination, regardless of the vaccine they received.
A 19-year-old adolescent with hereditary angioedema (HAE) successfully received a kidney transplant from his mother, who also had HAE, without experiencing a swelling attack either during or immediately after surgery, according to a case report in Argentina. Both received preventive treatment before and after the procedure and fresh frozen…
People with drug-induced nonallergic angioedema caused by aspirin who have had a heart attack may still be able to receive aspirin after undergoing desensitization soon after emergency treatment, a case report from France showed. Aspirin desensitization involves giving gradually increasing aspirin doses under close medical supervision until the patient…
A medication commonly used to treat nausea after surgery and allergic reactions triggered angioedema of the intestine (intestinal angioedema) in a woman recovering from stomach cancer surgery, according to a case report. The woman’s angioedema symptoms and imaging findings resembled those of potentially life-threatening gastrointestinal complications that may…
In seven cases involving people with hereditary angioedema (HAE) who had challenges with existing treatment options, doctors in Italy reported generally good disease control, adherence or treatment satisfaction after patients started oral Orladeyo (berotralstat). The cases covered three…
People with hereditary angioedema (HAE) who have limited access to on-demand medications for swelling attacks are more likely to delay or avoid treatment — and report poorer disease control and quality of life — than those for whom meds are readily available, according to a real-world survey of nearly…
The U.S. Food and Drug Administration has accepted Pharvaris’ application seeking approval of the immediate-release (IR) formulation of deucrictibant as an oral, on-demand treatment for hereditary angioedema (HAE) swelling attacks. The New Drug Application (NDA) includes data from the treatment of more than 1,300 HAE attacks across a…
A five-minute educational video designed to help healthcare professionals recognize and respond to life-threatening hereditary angioedema (HAE) attacks improved nursing students’ knowledge, confidence, and motivation to care for patients in a pilot U.K. study. Researchers hope the tool could ultimately improve emergency care for people with HAE, who often…
Recent Posts
- Bruise-like facial swelling leads to HAE diagnosis in 7-year-old girl
- Better understanding the HAE attack triggers in our lives
- Informed doctors help patients navigate HAE treatment options
- COVID-19 vaccines may produce distinct immune responses in HAE
- Kidney transplant between mother and son with HAE succeeds: Case report