News

In seven cases involving people with hereditary angioedema (HAE) who had challenges with existing treatment options, doctors in Italy reported generally good disease control, adherence or treatment satisfaction after patients started oral Orladeyo (berotralstat). The cases covered three…

People with hereditary angioedema (HAE) who have limited access to on-demand medications for swelling attacks are more likely to delay or avoid treatment — and report poorer disease control and quality of life — than those for whom meds are readily available, according to a real-world survey of nearly…

The U.S. Food and Drug Administration has accepted Pharvaris’ application seeking approval of the immediate-release (IR) formulation of deucrictibant as an oral, on-demand treatment for hereditary angioedema (HAE) swelling attacks. The New Drug Application (NDA) includes data from the treatment of more than 1,300 HAE attacks across a…

A five-minute educational video designed to help healthcare professionals recognize and respond to life-threatening hereditary angioedema (HAE) attacks improved nursing students’ knowledge, confidence, and motivation to care for patients in a pilot U.K. study. Researchers hope the tool could ultimately improve emergency care for people with HAE, who often…

About 1 in 7 treated swelling attacks in people with hereditary angioedema (HAE) required an additional dose of on-demand medication, with attack severity and treatment characteristics emerging as the main factors associated with retreatment, according to a real-world study from the Czech Republic that examined more than 8,000…

People with hereditary angioedema (HAE) have a higher risk of developing post-traumatic stress disorder (PTSD), a mental health condition triggered by exposure to psychological stress, according to a new study. Researchers also found that a PTSD diagnosis correlated with high rates of depression and reduced mental health-related quality of…

An international registry collecting real-world data from people with recurrent angioedema — marked by repeated swelling episodes — has enrolled more than 500 patients across 18 countries in its first two years, according to a new study. The database’s rapid expansion shows it’s already becoming “a robust global real-world…

The Angioedema Quality of Life Questionnaire (AE-QoL) is a reliable and effective tool for measuring the impact of hereditary angioedema (HAE) on patients’ day-to-day lives — and can also detect meaningful improvements when the genetic disease becomes better controlled. That’s according to an analysis of data from OASIS HAE…

The investigational therapy barzolvolimab rapidly reduced angioedema in people with chronic spontaneous urticaria (CSU) in a Phase 2 trial, and many remained free of swelling months after treatment ended. At the trial’s final assessment, conducted at week 76 (about 17.5 months after the study began), as many as 64%…

Children and young adults with angioedema rarely require airway management to ensure an open passage for airflow, but when they do, it usually indicates more severe disease associated with longer hospital stays, higher costs, and a greater risk of death. Those are the findings of a new study by…