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Specialists treating hereditary angioedema (HAE) across Latin America largely agree with international treatment guidelines, but high costs, limited access to medications, and frequent supply interruptions may keep patients from getting the care they need, a survey has found. Nearly two-thirds of the 30 specialists surveyed across 10 countries reported…

A 73-year-old man with influenza A, the major cause of seasonal flu, developed sudden upper-lip swelling about one hour after taking the antiviral Tamiflu (oseltamivir), raising suspicion that the medicine may have triggered angioedema, according to a case report. After Tamiflu was stopped, the swelling gradually improved and resolved…

Nearly one in five people with hereditary angioedema (HAE) left their latest swelling attack untreated, most often because it seemed mild or did not limit their activities, an international survey has found. Preventive treatment brought its own challenges, as forgetting doses and difficulty fitting medication into daily routines were…

Long-term preventive therapy can keep people with hereditary angioedema (HAE) free from swelling attacks requiring treatment for extended periods, according to a real-world study in Germany that found that more than one-third of HAE patients on prophylactic meds had no attacks needing on-demand treatment for at least one year.

The experimental therapy barzolvolimab can reduce disease activity in people with chronic spontaneous urticaria (CSU) — an inflammatory disorder characterized by recurrent itching and hives — who experience angioedema, according to results from two Phase 3 clinical trials. Celldex Therapeutics, the company developing barzolvolimab, plans to use the…

Dawnzera (donidalorsen), a preventive therapy used to reduce the risk of swelling attacks in people with hereditary angioedema (HAE), has been approved in Canada for adults and adolescents ages 12 and older. The decision by Health Canada follows Dawnzera’s approval for the same indication in the U.S. last…

Hereditary angioedema (HAE) should be considered in children with recurrent severe abdominal pain and vomiting, especially when such episodes are separated by complete recovery or accompanied by unexplained swelling. That’s the recommendation of a team of researchers in Argentina, who treated a young boy with recurring severe pain who…

New trial data show that BW-20805, Argo Biopharma‘s long-acting injection therapy for hereditary angioedema (HAE), continues to substantially reduce swelling attacks among adults with HAE for as long as six months after treatment. These findings come from a larger group of people with HAE taking part in the…

Lower blood levels of an enzyme involved in processes such as tissue remodeling and wound healing may help distinguish people with idiopathic angioedema, a form of angioedema that has no obvious cause, from those with hereditary angioedema (HAE) or mast cell-mediated angioedema, a small study in China suggested. Levels…

Once-daily treatment with deucrictibant extended-release (XR) tablets reduced the frequency of swelling attacks among people with hereditary angioedema (HAE) by more than 80% compared with a placebo in a late-stage clinical trial. Moreover, lasting benefits were seen for study participants with different types of the chronic genetic disease.