News

For people with hereditary angioedema (HAE), regardless of a person’s racial or ethnic background, living with this chronic disease can take a toll on emotional well-being and cause difficulty engaging in day-to-day activities, a new study found. The research specifically examined non-white patients, addressing a gap in earlier studies…

Biocryst Pharmaceuticals will present new clinical trial and real-world data on its treatments for hereditary angioedema (HAE) at this year’s American Academy of Allergy, Asthma & Immunology (AAAAI) annual meeting, the company announced. The data include six abstracts reporting updated findings on Orladeyo (berotralstat), an approved oral…

Using Takhzyro (lanadelumab) cut monthly swelling attacks by about 80% in newly treated people with hereditary angioedema (HAE) in Canada, and helped maintain low attack rates among those already on the therapy. Further, the injection treatment was generally well tolerated, with no serious side effects reported. These findings come…

People with type 3 hereditary angioedema (HAE) may report more frequent swelling attacks than people with HAE types 1 or 2, according to a new survey study. The findings also suggest people with HAE type 3 may be more likely to experience potentially life-threatening throat swelling and to report…

Adults with hereditary angioedema (HAE) experience physical stress responses similar to those with other chronic conditions, such as the autoimmune condition immune thrombocytopenia (ITP), in which stress is usually not involved in disease flare-ups. A new study found that when faced with stressful tasks, HAE patients showed heart…

Biocryst Pharmaceuticals has acquired Astria Therapeutics, and with it navenibart, an investigational treatment to prevent swelling attacks in people with hereditary angioedema (HAE). Navenibart is being tested in the Phase 3 ALPHA-ORBIT trial (NCT06842823), which is recruiting patients, ages 12 and older with HAE type…

A 54-year-old man with sudden, unexplained abdominal pain was diagnosed with intestinal angioedema — marked by swelling of the gastrointestinal tract — linked to the use of the common blood pressure drug lisinopril, according to a case report. His symptoms resolved quickly after stopping treatment with the medication,…

The case of a new mother who developed severe acute allergic angioedema triggered by a common antibiotic was described by researchers in India in a new report, with the team seeking to stress the importance of early and “aggressive” treatment of reactions to even routinely used drugs. The woman,…

Dawnzera (donidalorsen), an injection therapy used to reduce the risk of swelling attacks in people with hereditary angioedema (HAE), has been approved in the European Union as a preventive treatment for HAE patients 12 and older. That decision, by the European Commission, comes shortly after the therapy was…

People with hereditary angioedema (HAE) began experiencing symptom relief from swelling attacks of the larynx (voice box) or abdomen in less than two hours after taking oral Ekterly (sebetralstat). The finding comes from an interim analysis of data from the open-label extension (OLE) study,…