Treatment with Xolair (omalizumab), an approved therapy for allergic asthma and chronic spontaneous urticaria (CSU), was associated with strong symptom control in people with mast cell–mediated angioedema, according to a large real-world study. Benefits were observed regardless of whether patients experienced wheals, itchy skin bumps commonly known as…
On-demand treatment with Ekterly (sebetralstat), marketed by Kalvista Pharmaceuticals for hereditary angioedema (HAE), reduced anxiety associated with swelling attacks more quickly and effectively than a placebo in a recent study. “Moderate-to-extreme anxiety was common,” the researchers wrote, but it eased with treatment, particularly in patients who were…
Deucrictibant, an experimental oral small molecule from Pharvaris, delivers rapid relief when used on demand for acute attacks of hereditary angioedema (HAE) and can, over time, also reduce the frequency of the swelling that causes the attacks,…
Discussion
One of the amazing perks of the organization I work for is that it often partners with the theater production company I own. Prior to the director’s tenure there, I’d been commissioned to produce many plays for him over the last 14 years. So, when he started this new position…
Angioedema is the formal medical term for swelling under the skin. It usually occurs as part of an allergic reaction, but has forms that are not due to allergies.
Acute angioedema often occurs as part of an allergic reaction to various allergens or triggers. These can include certain foods, insect bites or stings, medications, and natural rubber products like latex.
Angioedema and hives often occur at the same time. However, angioedema causes large, thick welts which may not be itchy, whereas hives are smaller and usually itchy.
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