Biocryst Pharmaceuticals has acquired Astria Therapeutics, and with it navenibart, an investigational treatment to prevent swelling attacks in people with hereditary angioedema (HAE). Navenibart is being tested in the Phase 3 ALPHA-ORBIT trial (NCT06842823), which is recruiting patients, ages 12 and older with HAE type…
Discussion
When stealing $150 million from some of the world’s most famous casinos, Danny Ocean knew the plan needed to be meticulous. In 2001’s iteration of “Ocean’s Eleven,” George Clooney’s character enacts revenge on one of his enemies by robbing the Bellagio, the Mirage, and the MGM Grand in Las Vegas.
A 54-year-old man with sudden, unexplained abdominal pain was diagnosed with intestinal angioedema — marked by swelling of the gastrointestinal tract — linked to the use of the common blood pressure drug lisinopril, according to a case report. His symptoms resolved quickly after stopping treatment with the medication,…
Discussion
A new year brings a familiar question: What now? For those of us living with a rare disease such as angioedema, the answer is rarely simple. We don’t get the luxury of clean starts or easy resolutions. What we do carry forward is knowledge. About our bodies, about the…
Angioedema is the formal medical term for swelling under the skin. It usually occurs as part of an allergic reaction, but has forms that are not due to allergies.
Acute angioedema often occurs as part of an allergic reaction to various allergens or triggers. These can include certain foods, insect bites or stings, medications, and natural rubber products like latex.
Angioedema and hives often occur at the same time. However, angioedema causes large, thick welts which may not be itchy, whereas hives are smaller and usually itchy.
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