Long-term preventive treatment with Takhzyro (lanadelumab-flyo) — approved in the U.S. and the European Union for nearly a decade — substantially reduces the rate of swelling attacks in people with hereditary angioedema (HAE) treated in routine clinical practice. That’s according to the final results of a Phase 4 study…
Discussion
An infant with recurrent episodes of swelling in her limbs and around her eyes was ultimately diagnosed with idiopathic angioedema after tests ruled out lymphedema and other potential causes, according to a case report. The 4-month-old girl was initially referred for evaluation for possible lymphedema, a condition in which…
Discussion
A woman with hereditary angioedema (HAE) gave birth to a healthy baby after being briefly exposed to Orladeyo  (berotralstat) early in her pregnancy, according to a case report from Italy. The woman became pregnant about three months after starting Orladeyo, and the fetus was exposed to the treatment…
Discussion
A 7-year-old girl in Iran with repeated episodes of unexplained swelling was ultimately diagnosed with hereditary angioedema (HAE) after bruise-like discoloration appeared around one eye and then developed into swelling on one side of her face, according to a case report. Laboratory testing confirmed that the girl had type…
Angioedema is the formal medical term for swelling under the skin. It usually occurs as part of an allergic reaction, but has forms that are not due to allergies.
Acute angioedema often occurs as part of an allergic reaction to various allergens or triggers. These can include certain foods, insect bites or stings, medications, and natural rubber products like latex.
Angioedema and hives often occur at the same time. However, angioedema causes large, thick welts which may not be itchy, whereas hives are smaller and usually itchy.
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