Long-term preventive treatment for hereditary angioedema (HAE) was associated with fewer swelling attacks requiring emergency or inpatient care, but many patients still struggle to remain on treatment and continue to experience a substantial disease burden, a claims-based real-world U.S. study reports. Among nearly 500 people who started preventive, or…
Discussion
For lack of a better phrase, and at the risk of sounding cliché, a summer job for a teenager is a time-honored tradition. It’s such a well-known trope that shows like “Saved by the Bell,” “The O. C.,” and “Stranger Things” have entire seasons dedicated to following teenagers as they…
Researchers for the first time have developed separate liver cell lines, each derived from people with hereditary angioedema (HAE), that accurately replicate the molecular and cellular processes underlying the condition. “These models not only exhibit key molecular features of HAE but also provide a versatile platform for mechanistic studies…
Note: This story was updated May 26, 2026, to correct the time until symptom relief and the two formulations being investigated. Deucrictibant began relieving symptoms within a median of 1.28 hours. Developer Pharvaris is testing both immediate-release capsules and extended-release tablets. Pharvaris plans to soon submit an application to…
Angioedema is the formal medical term for swelling under the skin. It usually occurs as part of an allergic reaction, but has forms that are not due to allergies.
Acute angioedema often occurs as part of an allergic reaction to various allergens or triggers. These can include certain foods, insect bites or stings, medications, and natural rubber products like latex.
Angioedema and hives often occur at the same time. However, angioedema causes large, thick welts which may not be itchy, whereas hives are smaller and usually itchy.
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