Local cytokine release syndrome (L-CRS) is a potentially underrecognized complication of CAR T-cell therapy for blood cancer that can appear as cervical angioedema, or swelling in the deeper layers of tissue in the neck or throat, a study suggests. The swelling may occur after a bodywide inflammatory response has…
Discussion
During the 1992-93 AFC Wild Card playoff game, the Houston Oilers faced off against the Buffalo Bills. In a twist on irony, the game was a rematch of that particular season’s ender, which the Oilers won. Adding to the mounting anxiety for Bills fans and players, their starting quarterback, Jim…
A six-month dosing regimen of Argo Biopharma‘s long-acting investigational therapy BW-20805 reduced monthly attacks in people with hereditary angioedema (HAE) by up to 99%. That’s according to new data from an ongoing open-label Phase 2 clinical trial (NCT06846398) testing the therapy in up to 25 adults, ages…
Discussion
Change happens, and it can be good, bad, or neutral. How we deal with it is the real challenge. Having a family like mine that deals with multiple rare diseases means constantly confronting many challenges. When one of the rare diseases in our family is angioedema, the challenges associated…
Angioedema is the formal medical term for swelling under the skin. It usually occurs as part of an allergic reaction, but has forms that are not due to allergies.
Acute angioedema often occurs as part of an allergic reaction to various allergens or triggers. These can include certain foods, insect bites or stings, medications, and natural rubber products like latex.
Angioedema and hives often occur at the same time. However, angioedema causes large, thick welts which may not be itchy, whereas hives are smaller and usually itchy.
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