The experimental therapy barzolvolimab can reduce disease activity in people with chronic spontaneous urticaria (CSU) — an inflammatory disorder characterized by recurrent itching and hives — who experience angioedema, according to results from two Phase 3 clinical trials. Celldex Therapeutics, the company developing barzolvolimab, plans to use the…
Discussion
Dawnzera (donidalorsen), a preventive therapy used to reduce the risk of swelling attacks in people with hereditary angioedema (HAE), has been approved in Canada for adults and adolescents ages 12 and older. The decision by Health Canada follows Dawnzera’s approval for the same indication in the U.S. last…
Discussion
Hereditary angioedema (HAE) should be considered in children with recurrent severe abdominal pain and vomiting, especially when such episodes are separated by complete recovery or accompanied by unexplained swelling. That’s the recommendation of a team of researchers in Argentina, who treated a young boy with recurring severe pain who…
Discussion
“But the most important rule … never feed him after midnight.” That was part of the ominous and infamous instructions for owning a mogwai in the 1984 thriller “Gremlins.” In the movie, Billy receives a pet for Christmas that comes with confusing and complicated verbal instructions. The cute little creature,…
Angioedema is the formal medical term for swelling under the skin. It usually occurs as part of an allergic reaction, but has forms that are not due to allergies.
Acute angioedema often occurs as part of an allergic reaction to various allergens or triggers. These can include certain foods, insect bites or stings, medications, and natural rubber products like latex.
Angioedema and hives often occur at the same time. However, angioedema causes large, thick welts which may not be itchy, whereas hives are smaller and usually itchy.
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