Chiesi has entered into a definitive agreement to acquire Kalvista Pharmaceuticals, and with it, Ekterly (sebetralstat), an oral on‑demand treatment for acute swelling attacks in people with hereditary angioedema (HAE). The transaction was approved by both companies’ boards of directors and is expected to be completed by the…
Discussion
Rare diseases usually don’t play nice with each other. They can land those of us who have them in a catch-22 scenario where it feels like we lose no matter what. I am one of many in this oh-so-lucky club of multiple rare diseases. I’ve been part of the…
Discussion
Several members of my family live with angioedema. My eldest daughter, Aria, has allergic angioedema; my son Dorian has hereditary angioedema (HAE) type 1; my adopted daughter, Leah, has HAE type 2; and I have HAE type 3, or HAEÂ with normal C1-INH. On top of angioedema, we…
A single dose of lonvoguran ziclumeran (lonvo-z) left more than 60% of patients with hereditary angioedema (HAE) free of swelling attacks and ongoing therapy during a six-month evaluation period, suggesting it could reduce the need for lifelong preventive therapy if approved. That is according to topline data from…
Angioedema is the formal medical term for swelling under the skin. It usually occurs as part of an allergic reaction, but has forms that are not due to allergies.
Acute angioedema often occurs as part of an allergic reaction to various allergens or triggers. These can include certain foods, insect bites or stings, medications, and natural rubber products like latex.
Angioedema and hives often occur at the same time. However, angioedema causes large, thick welts which may not be itchy, whereas hives are smaller and usually itchy.
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