KalVista Pharmaceuticals‘ investigational therapy KVD900 for the treatment of hereditary angioedema (HAE) rapidly reduces the activity of plasma…
Joana Carvalho, PhD
Joana holds a bachelor’s in biology, a Master of Science in evolutionary and developmental biology, and a PhD in biomedical sciences from Universidade de Lisboa, Portugal. Her work has been focused on the impact of non-canonical Wnt signaling in the collective behavior of endothelial cells — those that make up the lining of blood vessels — found in the umbilical cord of newborns. In addition to several research fellowships, she was awarded two Erasmus scholarships to conduct part of her studies in France.
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Articles by Joana Carvalho, PhD
Prophylactic (preventative) treatment with Cinryze reduced the number and severity of attacks in young children with hereditary angioedema (HAE),…
Takhzyro (lanadelumb), an antibody already approved for routine prevention of hereditary angioedema (HAE) attacks in patients ages 12 and…
Angiotensin-converting enzyme (ACE) activity levels can vary among different donors of fresh frozen plasma (FFP) — commonly used for the treatment of…
A recently described mutation in the plasminogen (PLG) gene has been reported in an additional family in Germany with hereditary…
The three prophylactic medicines currently on the market for hereditary angioedema (HAE) — the C1 esterase inhibitors Cinryze and Haegarda, and Takzyhro…
Intestinal hereditary angioedema (HAE) should be considered as a possible cause of abdominal pain, even in patients with normal C1…
Despite being more prone to developing heart disease, patients with hereditary angioedema with C1 inhibitor deficiency (C1-INH-HAE) show…
Ruconest (recombinant C1-inhibitor, rhC1-INH) and Firazyr (icatibant) are safe and effective approaches as first-line treatment for hereditary angioedema (HAE) attacks in…
Mother’s Diagnosis of Daughter’s HAE Highlights Need for Clinicians to Listen to Patients, Families
The mother of a 28-year old pregnant woman suspected her daughter had hereditary angioedema after doing an internet search while the…