The Committee for Medicinal Products for Human Use (CHMP), an arm of the European Medicines Agency, has recommended the approval of Takhzyro (lanadelumab) for the routine prevention of hereditary angioedema (HAE) attacks in children starting at age 2. Based on a positive opinion from the CHMP, the European…
A 46-year-old man developed delayed angioedema following surgery — with his tongue swelling significantly four hours later — that likely was triggered by the use of an ACE or angiotensin-converting enzyme inhibitor to treat his high blood pressure, according to a new case report. Due to rapid evaluation by…
Pediatricians in Brazil show, in general, a low level of knowledge of hereditary angioedema (HAE), according to a recent study. Even though those who were board-certified specialists in allergy and immunology were more knowledgeable than those who weren’t, their level of knowledge was still considered unsatisfactory. “Based on the…
The use of long-term preventive treatment among people with hereditary angioedema (HAE) was found to significantly reduce the rate of swelling attacks for patients in six countries, according to a new study conducted in North America, Europe, and Australia. Considering the effectiveness of long-term prophylaxis in preventing HAE attacks,…
A 22-year-old woman with systemic lupus erythematosus (SLE), the most common form of lupus, developed acquired angioedema (AAE), a recent case report notes. “AAE may happen in adolescents and young adults. It could be an early manifestation of SLE,” the researchers wrote, adding that “practitioners must be aware…
Nearly half of hereditary angioedema (HAE) patients in the U.K. are on long-term prophylactic treatment to prevent swelling attacks, with more than 80% keeping a supply of on-demand therapies at home to treat sudden flares. That’s according to data from a new national survey that also provided information on…
Hereditary angioedema (HAE) Awareness Day is an annual global event held each May 16 to call attention to the disease, which is estimated to affect 1 in 50,000 to 150,000 people worldwide. The day focuses on activities that unite the HAE community and raise awareness among the general…
A 48-year-old man developed angioedema after taking losartan, a medication commonly used to treat high blood pressure, a U.S. case study reported. Losartan, sold under the brand name Cozaar, is used to manage cardiovascular conditions, including lowering the risk of stroke with heart disease. To date, 20 reports have…
The use of preventive therapy in hereditary angioedema (HAE) was found to reduce the number of HAE attacks requiring on-demand treatment, and also had an impact on productivity, with patients losing fewer work or school days, a study in Australia reported. However, prophylactic treatment did not seem to ease…
A substantial proportion of adults with hereditary angioedema (HAE) in the Netherlands have poorly controlled disease, significantly affecting their quality of life, a survey study reported. Findings also linked well-controlled HAE to lower medical costs and greater productivity, relative to patients without adequate disease control. “Additional [preventive treatment] strategies…
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