Deletion mutations in the SERPING1 gene lead to lower function levels of the C1 inhibitor protein, which, in turn, might have a negative impact on the progression and severity of hereditary angioedema (HAE), a study reveals. The study, “Deletions in SERPING1 Lead to Lower C1 Inhibitor Function:…
Hereditary angioedema (HAE) can present itself as a sudden and severe abdominal pain, even in the absence of other typical symptoms, such as swelling in the skin and mucosal linings, a case study from Japan has found. According to the authors, physicians should not overlook these uncharacteristic symptoms and…
Researchers from University of Chicago Medicine reported the case of a patient who developed orolingual angioedema after the administration of alteplase (sold under the brand name Activase), and suggest how physicians should proceed in case of an emergency. The study, “A Case Report of Unilateral Orolingual Angioedema…
Researchers have developed a new way to distinguish bradykinin-mediated angioedema from histamine-mediated angioedema. This biomarker tool may improve the use of targeted therapies in angioedema patients. The study, “Threshold‐Stimulated Kallikrein Activity Distinguishes Bradykinin‐ From Histamine‐Mediated Angioedema,” was published in Clinical & Experimental Allergy. Angioedema encompasses…
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