Types of Angioedema

Acute allergic angioedema refers to a form of angioedema that occurs as a result of an allergic reaction. It is marked by swelling that is usually accompanied by hives and other allergy-related symptoms. Substances that can act as triggers for this type of angioedema include certain foods, medications, latex, and venom from insect bites.

Acquired angioedema is a rare type of angioedema that’s commonly associated with an underlying illness, such as cancer or an autoimmune disease. Like other types of angioedema, acquired angioedema is characterized by swelling attacks that can occur anywhere in the body. Swelling in this type of angioedema is caused by a C1-INH deficiency.

Hereditary angioedema is a type of angioedema that is caused by genetic mutations that are usually inherited from a person’s biological parents. Similar to other forms of angioedema, it is marked by recurrent swelling episodes that can occur anywhere in the body. Swelling in this type of angioedema is driven by the overproduction of a signaling molecule called bradykinin and is usually not accompanied by hives or an itchy rash.

Idiopathic angioedema is a form of angioedema that has no obvious cause or trigger. Similar to other types of angioedema, its hallmark symptom is swelling, which most commonly occurs in the face, limbs, and extremities.

Nonallergic angioedema is a type of angioedema that occurs due to an adverse reaction to certain medications. Like other types of angioedema, it is marked by swelling. Angiotensin converting enzyme (ACE) inhibitors, which are commonly used to treat high blood pressure, are the most notable class of medicines that can trigger nonallergic angioedema.